ethyl 2-aMinopyridin-3-carboxylate
Ethyl 2-aminopyridine-3-carboxylate
CAS: 13362-26-0
Molecular Formula: C8H10N2O2
ethyl 2-aMinopyridin-3-carboxylate - Names and Identifiers
| Name | Ethyl 2-aminopyridine-3-carboxylate |
| Synonyms | AKOS 90517 RARECHEM AL BI 1234 ETHYL 2-AMINONICOTINATE Ethyl 2-aMinonicotinic acid Nicotinic acid Impurity 10 2-Amino-3-carbethoxypyridine 2-Amino-3-(ethoxycarbonyl)pyridine 2-AMINO-NICOTINIC ACID ETHYL ESTER ethyl 2-aMinopyridin-3-carboxylate Ethyl 2-amino-3-pyridinecarboxylate Ethyl 2-aminopyridine-3-carboxylate |
| CAS | 13362-26-0 |
| InChI | InChI=1/C8H10N2O2/c1-2-12-8(11)6-4-3-5-10-7(6)9/h3-5H,2H2,1H3,(H2,9,10) |
ethyl 2-aMinopyridin-3-carboxylate - Physico-chemical Properties
| Molecular Formula | C8H10N2O2 |
| Molar Mass | 166.18 |
| Density | 1.192±0.06 g/cm3(Predicted) |
| Melting Point | 96-98°C |
| Boling Point | 133°C/12mmHg(lit.) |
| Flash Point | 115.126°C |
| Solubility | DMSO, Methanol |
| Vapor Presure | 0.008mmHg at 25°C |
| Appearance | Solid |
| Color | Yellow |
| pKa | 4.84±0.36(Predicted) |
| Storage Condition | Keep in dark place,Inert atmosphere,Room temperature |
| Refractive Index | 1.559 |
| MDL | MFCD01569452 |
ethyl 2-aMinopyridin-3-carboxylate - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. |
| HS Code | 29339900 |
| Hazard Class | IRRITANT |
ethyl 2-aMinopyridin-3-carboxylate - Introduction
Ethyl 2-aminonicotinate is an organic compound with the chemical formula C7H9N3O2. The following is an introduction to some of the properties, uses, preparation methods and safety information of 2-aminonicotinic acid ethyl ester:
Nature:
-Appearance: Ethyl 2-aminonicotinate is a white crystalline powder.
-Melting point: about 140-143 degrees Celsius.
-Solubility: Ethyl 2-aminonicotinate is soluble in water.
-Chemical reaction: 2-amino nicotinic acid ethyl ester can be oxidized by the action of oxidizing agent.
-Storage conditions: should be stored in a dry, cool place, away from fire and oxidizing agents.
Use:
-Pharmaceutical field: Ethyl 2-aminonicotinate is commonly used as a pharmaceutical intermediate, such as the synthesis of cephalosporin antibiotics and other drugs.
-Cosmetics field: 2-Aminonicotinic acid ethyl ester is widely used in cosmetics as a component of sunscreen, antibacterial agent, moisturizer, etc.
Preparation Method:
-Ethyl 2-aminonicotinate is often prepared by transesterification between ethanolamine and pyridine.
-During the reaction, 2-aminonicotinic acid is reacted with acetic anhydride or acetic acid chloride to generate 2-aminonicotinic acid ethyl ester.
Safety Information:
-2-Aminonicotinic acid ethyl ester should be kept away from open flames and high temperatures, and avoid contact with oxidants.
-Wear appropriate chemical-resistant protective gloves and goggles when exposed. Good ventilation should be paid attention to during operation and storage.
-In case of skin contact or inhalation, rinse immediately with water and seek medical treatment.
Nature:
-Appearance: Ethyl 2-aminonicotinate is a white crystalline powder.
-Melting point: about 140-143 degrees Celsius.
-Solubility: Ethyl 2-aminonicotinate is soluble in water.
-Chemical reaction: 2-amino nicotinic acid ethyl ester can be oxidized by the action of oxidizing agent.
-Storage conditions: should be stored in a dry, cool place, away from fire and oxidizing agents.
Use:
-Pharmaceutical field: Ethyl 2-aminonicotinate is commonly used as a pharmaceutical intermediate, such as the synthesis of cephalosporin antibiotics and other drugs.
-Cosmetics field: 2-Aminonicotinic acid ethyl ester is widely used in cosmetics as a component of sunscreen, antibacterial agent, moisturizer, etc.
Preparation Method:
-Ethyl 2-aminonicotinate is often prepared by transesterification between ethanolamine and pyridine.
-During the reaction, 2-aminonicotinic acid is reacted with acetic anhydride or acetic acid chloride to generate 2-aminonicotinic acid ethyl ester.
Safety Information:
-2-Aminonicotinic acid ethyl ester should be kept away from open flames and high temperatures, and avoid contact with oxidants.
-Wear appropriate chemical-resistant protective gloves and goggles when exposed. Good ventilation should be paid attention to during operation and storage.
-In case of skin contact or inhalation, rinse immediately with water and seek medical treatment.
Last Update：2024-04-09 02:00:42
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Product Name: Ethyl 2-Aminopyridine-3-Carboxylate Visit Supplier Webpage Request for quotationCAS: 13362-26-0
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
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